Author summary Onchocerciasis, or river blindness, is a parasitic disease transmitted by blackflies. It remains a public health challenge in parts of Ghana despite decades of community treatment with ivermectin. In Kwanware-Ottou area within the Wenchi Health District, transmission has persisted for over 27 years. This study investigated why onchocerciasis continues to spread in this region and tested new strategies to improve treatment coverage. Using satellite imagery, community mapping and interviews, we identified hard-to-reach settlements and population groups often missed during treatment. A locally tailored action plan was developed and implemented with strong community involvement. Results showed a significant increase in treatment coverage and improved community participation. This approach demonstrates how combining local knowledge, technology, and participatory planning can help overcome persistent disease transmission. These findings offer a practical model for other regions facing similar challenges in eliminating onchocerciasis and other neglected tropical diseases.
Background
Onchocerciasis, also commonly known as river blindness, is a neglected tropical disease (NTD), endemic in Ghana and many other sub-Saharan African countries. The disease is caused by a parasitic worm called Onchocerca volvulus transmitted … [33884 chars]
Source: PLOS (Public Library of Science) | Published: 2026-02-05T00:00:00Z
Credit: PLOS (Public Library of Science)
